N-[3-(tert-Butyldimethylsiloxymethyl)-5-nitrophenyl]acetamide

N-[3-(tert-Butyldimethylsiloxymethyl)-5-nitrophenyl]acetamide

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The title compound, C15H24N2O4Si, was prepared by the reaction of (3-acetamido-5-nitrobenzyl)methanol with tert-butyldimethylsilyl chloride and is boss ga fc ex a key intermediate in the synthesis of novel nonsymmetrical DNA minor groove-binding agents.There are two independent molecules in the structure, which differ primarily in the rotation about the C—O bond next to the hp 27xq Si atom.Two strong N—H.

O hydrogen bonds align the molecules into a wide ribbon extending approximately parallel to the b axis.